2005•Faculty Opinions – Post-Publication Peer Review of the Biomedical LiteratureRequires access

Faculty Opinions recommendation of Efficacy of caspofungin against Aspergillus terreus.

Thomas F. Patterson

Abstract

We investigated the in vitro and in vivo activities of caspofungin against Aspergillus terreus. The drug increased survival and reduced tissue fungal burden in neutropenic mice. Therefore, our data support the role of caspofungin in treating systemic infections due to this emerging pathogen. PMID: 16304185

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Available abstract

Key concepts: Caspofungin, Aspergillus terreus, Aspergillus, In vivo, Fungal pathogen, Microbiology, Biology, Aspergillosis