Influence of Central Corneal Thickness (CCT) on Intraocular Pressure (IOP) Measured with Goldmann Applanation Tonometer (GAT) in Normal Individuals

Purpose: This study investigated the relationship between intraocular pressure (IOP) and central corneal thickness (CCT) in normal healthy individuals. Material and Methods: The central corneal thickness (CCT) and intraocular pressure (IOP) of 250 subjects (500 eyes) of age 11-54 years from general population were assessed. The IOP was measured with Goldmann applanation tonometer (GAT) and CCT was measured with Orbscan II scanning slit topographer. The relationship was assessed using SPSS software. Results: The mean IOP value was 15.35 mmHg and mean CCT value was 531.50 μm in 250 subjects (500). The mean IOP value was 15.16 mmHg SD ± 2.89 mmHg in men and 15.53 mmHg SD ± 3.11 mmHg in women. The mean CCT value was 529.07 μm SD ± 35.19 μm in men and 533.75 μm SD ± 38.11 μm in women. No significant difference in CCT and IOP was found between male and female subjects or between the right and left eye. Both genders had positive correlation between CCT and IOP. Conclusion: CCT was significantly correlated with IOP.