2000•Unpublished venueRequires access

Protective Effect of XinXin Capsule on learning and Memory Impairment in Mice

Gui-you Du

Abstract

Objective: To investigate the effect of Xinxin Capsule on the scopolamine or ethanol induced impairment of learning and memory retention in mice. Method: Step-through and Morris Water-maze methods, wer used to the protective effect of Xinxin Capsule(0.4,0.8,1.6 g·kg -1 ,ig,16 d) on the scopolamine or ethanol induced impairment of learning and memory retention in mice. Result:The Capsule(0.8,1.6 g·kg -1 ,ig,)can turn over the Scop so as to induce the impairment of learning, and the Capsule((0.4,0.8,1.6 g·kg -1 ,ig) can improve the ethanol induced impairment of memory retention in mice. Conclusion:Xinxin Capsule helps regain as well as impair the learning and memory retention in mice.[

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Key concepts: Capsule, Memory impairment, Ethanol, Scopolamine, Morris water navigation task, Memory retention, Psychology, Medicine