Analysis of Clinical and Spermatic Factors on Pregnancy Rate of Intrauterine Insemination

Objective To evaluate the effect-relative factors on pregnancy rate after intrauterine insemination (IUI) by analyzing the clinical data of patients receiving IUI with husband sperm. Methods Clinical data of 213 infertile couples who received IUI in Yunnan Population and Family Planning Research Institute from January 2009 to September 2011 were selected, and 298 cycles were included. This study followed the ethical standards which formulated by Yunnan Population and Family Planning Research Institute, approved by the committee. The relationship between clinical factors, including maternal age, infertile time, infertile type, ovulation induction protocol, processed total motile sperm count(PTMS) and pregnancy rate were analyzed. Results The pregnancy rate in the group of 0.05). The pregnancy rate of the patients ≥40 years old decreased significantly (χ2=179, P 10×106/mL were significantly difference (χ2=596, P<0.05). Conclusions In the course of IUI with husband sperm, female age, infertile time, primary or secondary infertility, ovulation induction protocol and PTMS could affect pregnancy rate. Key words: processed total motile sperm count; intrauterine insemination; pregnancy rate