Analysis of Clinical and Spermatic Factors on Pregnancy Rate of Intrauterine Insemination

Objective To evaluate the effect-relative factors on pregnancy rate after intrauterine insemination(IUI)by analyzing the clinical data of patients receiving IUI with husband sperm.Methods Clinical data of 213infertile couples who received IUI in Yunnan Population and Family Planning Research Institute from January 2009to September 2011were selected,and 298cycles were included.This study followed the ethical standards which formulated by Yunnan Population and Family Planning Research Institute,approved by the committee.The relationship between clinical factors,including maternal age, infertile time,infertile type,ovulation induction protocol,processed total motile sperm count(PTMS)and pregnancy rate were analyzed.Results The pregnancy rate in the group of30,30-34and 35-39were not significant(χ2=4.58,P0.05).The pregnancy rate of the patients≥40years old decreased significantly(χ2=179,P0.05).The pregnancy rate of the patients with infertile time≥5years was more higher than that of infertile time2years and 3-4years(χ2=298,P0.05).The pregnancy rate of the patients with secondary infertility was significantly higher than that of the patients with primary infertility(χ2=578,P 0.05).The pregnancy rate in the groups of PTMS5×106/mL,(5-10)×106/mL,10×106/mL were significantly difference(χ2=596,P0.05).Conclusions In the course of IUI with husband sperm,female age,infertile time,primary or secondary infertility,ovulation induction protocol and PTMS could affect pregnancy rate.