Analysis on clinical factors related to artificial insemination with husband sperm in 1382 cycles

Objective:To analyze the clinical data of patients receiving intrauterine insemination with husband sperm,evaluate the effect of relative factors on pregnancy rate after intrauterine insemination. Methods:943 infertile couples who received intrauterine insemination in the hospital from January 2007 to March 2009 were selected,1 382 cycles were included.The relationship between clinical factors including maternal age,infertile time,infertile causes,cycles of intrauterine insemination,ovulation induction protocol and pregnancy rate was analyzed. Results:The pregnancy rate of the patients more than 40 years decreased significantly(P0.05).The pregnancy rate of the patients with infertile time10 years decreased significantly(P0.05).The pregnancy rate of the patients with secondary infertility was significantly higher than that of the patients with primary infertility(P0.05).Among female factors,the pregnancy rate of the patients with polycystic ovary syndrome was the highest,the pregnancy rate of the patients with endometriosis was the lowest;among male factors,the pregnancy rate of the patients with sexual dysfunction and poor semen liquefaction was the highest,the pregnancy rate of the patients with teratozoospermia was 0.The pregnancy rate of ovulation induction cycles was higher than that of nature cycles,but there was no significant difference. Conclusion:In the course of intrauterine insemination with husband sperm,age,infertile time,infertile types,infertile causes and ovulation induction protocol can affect pregnancy rate,the effects of various factors should be considered comprehensively in the process of therapy.