Determination of β-HCG and progesterone for diagnosis of ectopic pregnancy

Objective To explore the diagnostic value of β-HCG and progesterone in ectopic pregnancy.Methods 60 patients with ectopic pregnancy were selected in women and children's hospital from February 2006 to February 2010 as the study group,60 patients with early intrauterine pregnancy as the control group 1 and 60 patients with missed abortion as the control group 2.Their β-HCG and progesterone are calculated for analysis.Results The β-HCG and progesterone of the control group 1 were higher than the other two groups(P0.05).There was no significant difference between study group and control group 2(P0.05).Taking progesterone≤9.33ng/ml of study group as a threshold,the diagnostic sensitivity、specificity、positive predictive value and negative predictive value of ectopic pregnancy were 87.51 %、78.92%、81.23% and 71.34% respectively.Combining the measurement of β-HCG and progesterone,the diagnostic sensitivity、specificity、positive predictive value and negative predictive value of ectopic pregnancy were 93.75 %、63.04%、89.94% and 67.06% respectively.Conclusion Combining the measurement of β-HCG and progesterone is significant to the early diagnosis of ectopic pregnancy.