2010Chinese Journal of Modern Drug ApplicationRequires access

The value of serum β-HCG and progesterone in the early diagnosis of ectopic pregnancy

Yang Guofe

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Abstract

Objective To explore the value of serum β-HCG and progesterone in the early diagnosis of ectopic pregnancy.Methods Serum β-HCG and progesterone were assayed of 46 cases were suspected to be ectopic pregnancy and 48 women who were intrauterine gestation.Results The serum β-HCG and progesterone value in ectopic pregnancy group were significantly lower than those in intrauterine gestation group(P0.01).When the cut-off point of progesterone was15ng/ml,the sensitivity and the specificity were 91.3% and 93.75% respectively,and the positive predictive value and negative predictive value were 93.3% and 91.8% respectively in the diagnosis of ectopic pregnancy.Conclusion Combined assaying Serum β-HCG with progesterone can enhance the sensitivity and the specificity in the diagnosis of ectopic pregnancy.

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Objective To explore the value of serum β-HCG and progesterone in the early diagnosis of ectopic pregnancy.Methods Serum β-HCG and progesterone were assayed of 46 cases were suspected to be ectopic pregnancy and 48 women who were intrauterine gestation.Results The serum β-HCG and progesterone value in ectopic pregnancy group were significantly lower than those in intrauterine gestation group(P0.01).When the cut-off point of progesterone was15ng/ml,the sensitivity and the specificity were 91.3% and 93.75% respectively,and the positive predictive value and negative predictive value were 93.3% and 91.8% respectively in the diagnosis of ectopic pregnancy.Conclusion Combined assaying Serum β-HCG with progesterone can enhance the sensitivity and the specificity in the diagnosis of ectopic pregnancy.

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Available abstract

Objective To explore the value of serum β-HCG and progesterone in the early diagnosis of ectopic pregnancy.Methods Serum β-HCG and progesterone were assayed of 46 cases were suspected to be ectopic pregnancy and 48 women who were intrauterine gestation.Results The serum β-HCG and progesterone value in ectopic pregnancy group were significantly lower than those in intrauterine gestation group(P0.01).When the cut-off point of progesterone was15ng/ml,the sensitivity and the specificity were 91.3% and 93.75% respectively,and the positive predictive value and negative predictive value were 93.3% and 91.8% respectively in the diagnosis of ectopic pregnancy.Conclusion Combined assaying Serum β-HCG with progesterone can enhance the sensitivity and the specificity in the diagnosis of ectopic pregnancy.

Key concepts: Ectopic pregnancy, Gestation, Medicine, Predictive value, Pregnancy, Obstetrics, Gynecology, Internal medicine

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