Value of progesterone monitoring in early diagnosis of ectopic pregnancy

Objective To explore the value of progesterone and serum β-HCG in the early diagnosis of ectopic pregnancy.Methods Progesterone and serum β-HCG were detected in 42 cases of suspected to be ectopic pregnancy and 40 women of regular intrauterine gestation.Results The progesterone and serum β-HCG value in the ectopic pregnancy group were obviously lower than those in the intrauterine gestation group,difference between the two groups showing statistical significance(P0.01).With progesterone 15 ng/mL as the cut-off point for diagnosing ectopic pregnancy,its sensitivity and the specificity were 90.48% and 92.50% respectively,the positive predictive value was 92.68% and the diagnosis coincidence rate was 91.46% in the diagnosis of ectopic pregnancy.Conclusion The united monitoring of progesterone and serum β-HCG can enhance the sensitivity and the specificity in the early diagnosis of ectopic pregnancy.