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Application of simvastatin in patients with acute coronary syndrome in early stage

Lin Liu

Abstract

Objective To observe the influence of simvastatin on blood lipid and C-reactive protein(CRP)in patients with acute coronary syndrome(ACS).Methods 60 patients were divided into treatment group with simvastatin and control groud without simvastatin.The treatment groud receive simvastatin 20mg/d.The blood lipid and C-reactive protein were measured before and after the treatment.30 healthy people were measured as healthy control group.Results Patients with Acs had higher levels of CRP than those of healthy control group.After simvastatin treatment,the levels of TC、TG 、LDL-C and CRP were significantly dceased.Conclusions simvastatin can reduce the levels of CRP and blood lipid evidently,has the effect of anti-inflammation and making plaque stable.

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Key concepts: Simvastatin, Medicine, Acute coronary syndrome, C-reactive protein, Internal medicine, Blood lipids, Cardiology, Inflammation