The discussion of serum D-dimer reference value examined by turbidimetric immunoassay

Objective To make the preliminary discussion of the serum D-dimer level in Normal popu-lation. Methods Serum D-dimer was detected by turbidimetric immunoassay on the Hitachi 7020 automatic bi-ochemistry analyzer. Results 338 apparently healthy controls were examined. The average value was 1.37 mg/ L,95% reference range 0. 1 ～ 2. 64 mg/L, assumes the normal distribution, male 165 examples, average value 1.28 mg/L,95% reference range 0. 15 ～2.41 mg/L; Female 173 examples,average value 1.46 mg/L,95% ref-erence scope 0. 04 ～ 2. 88 mg/L; In the healths controls, there was significantly deference of serum -dimer lev-el between the male and the female(P 0. 05) ; Compares with serum and heparin plasma, or the serum tube made by different country(Japan and China) , the difference has the extremely remarkable sta-tistics significance(P < 0. 001). Conclusion Preliminary defined the 95% reference value of serum D-dimer concentration was 0.1 ～2.64 mg/L; The serum and the heparin plasma D-dimer reference scope cannot use in common, but the relevance is good. Key words: Serum D-dimer; Normal population; Turbidimetric immunoassay