Analysis of bacterium distribution and drug resistance of acute hand injuries

Objective To understand bacterium distribution and drug resistance of the acute hand injuries.Methods The samples from 521 hand injury patients who were received in Hangzhou Plastic Surgery Hospital between June 2008 and June 2011 were taken germiculture and antibiotic susceptibility.Results A total of 99 strains of bacteria were isolated from 521 samples.There were 77 strains of gram-positive cocci (77.8％) and 22 strains of gram-negative bacilli(22.2％ ).There were 37 strains of Staphylococcus aureus and 22 strains of Staphylococcus epidermidis in grampositive cocci.In gram-negative bacilli,the most common pathogen was Pseudomonas aeruginosa( 13 strains),the next was Escherichia coli(5 strains).The resistance rate of gram-positive cocci to clindamycin and oxacillin was 26.0％ and 39.0％ separately,and the resistance rate to vancomycin,nitrofurantoin and linezolid was 0.The resistance rate of gramnegative bacilli resistant to ciprofloxacin and cefotaxime were 9.1％ and 13.6％.The resistance rate to imipenem,meropenem resistance rate was 0.Conclusions The main bacterium infection of acute hand injury patients was grampositive cocci.The vancomycin,nitrofurantoia and linezdid are still effective to gram-positive cocci.The carbapenem antibiotics have the best susceptibility to gram-negative bacilli. Key words: Bacteria; Acute hand injuries; Microbial sensitivity tests