Variation and drugs susceptibility of pathogenic bacteria from 2006 to 2008 in our hospital

Objective:To evaluate the variation and drugs susceptibility of pathogenic bacteria over 3 years in our hospital.Methods:A total of 1 175 strains of pathogens were analyzed statistically by retrospective study.Results:Among 1 175 strains of pathogens,235 were gram-positive cocci(20.00%);910 were gram-negative bacilli(77.45%) and 30 were fungi(2.55%).In 3 years,the average resistance rate of gram-positive cocci to penicillin,oxacillin,cefazolin,erythromycin and ciprofloxacin were most high.The average resistance rate of gram-negative bacilli to cefotaxime,cefepime,co-trimoxazole and ciprofloxacin were most high.Respectively the detection rate of Staphyloccocus bacteria producting β-lactamase to penicillin and amoxicillin were 85.71% in 2006 and 89.80% in 2007.Conclusion:In 3 years,gram-negative bacilliin strains causing hospital nosocomial infections increased,gram-positive cocci strains remain stable,but fungous infection showed a decline tendency.In view of the increasing drug resistance,rational use of antimicrobial agents should be stressed in the clinic.