Imaging distribution characteristics of cerebral infarction with diabetes mellitus

Objective To investigate the distribution of infarction in the population of cerebral infarction with diabetes mellitus and its influence factors. Methods ⑴ A total of 606 hospitalization patients of acute cerebral infarction was divided into cortical infarction, centrum ovale infarction, basal ganglion infarction and posterior infarction according to brain magnetic resonance imaging (MRI). The sex, age, biochemical marker and coexist with hypertension, diabetes mellitus or not were recorded. ⑵ The distribution difference of subtype infarction between with and without diabetes was compared, so did the positive rate of diabetes among different subtype infarction. The correlation between subtype infarction and diabetes was analyzed, and the level-risk relationship of subtype infarction was performed through logistic regression. Results ⑴ There existed obvious difference in the constituent ratio of cortical infarction, centrum ovale infarction, basal ganglion infarction and posterior infarction between with and without diabetes (χ2=19.795, P=0.000), percent of posterior infarction in diabetes group was higher than that in non-diabetes group (χ2=18.71, P<0.01). Among the infarction subtypes, positive rate of diabetes was obvious different, highest percent was existed in posterior infarction group [47 % (76/163)]. ⑵ Posterior infarction was correlated with diabetes, with the value of r and P was 0.176 and 0.000. ⑶ Logistic regression between posterior infarction and diabetes demonstrated that OR (95 % CI) was 2.247 (1.551~3.257), it changed to 1.898 (1.213~2.968) when adjusted by relative risk factors, and both of the P value were below 0.05. Conclusions Posterior infarction was more prone to occur in the population of cerebral infarction with diabetes, diabetes was the independent risk factor of posterior infarction. Key words: Diabetes mellitus/RA; Brain infarction/CO/RA; Magnetic resonance imaging