2011•Zhongguo jiceng yiyaoRequires access

The correlation and clinical significance of HBV infection makers

Jiayang Qiu, Liangjun Li, Fan Yang

Abstract

Objective To explore the internal relations of HBV markers and its clinical significance.Methods HBV Pre S1-Ag、HBV-M(HBsAg、HBsAb、HBeAg、HBeAb、HBcAb)and HBV DNA of 106 patients were detected by ELISA and FQ-PCR respectively.Results The total positive rates of Pre-S1 antigen and HBV DNA in 106 cases were 81.1%and 84.9%respectively.In41 HBeAg-positive cases.Pre S1-Ag and HBV DNA detection rate was 95.1%.90.2%.And HBeAg-negative 2 groups Pre S1-Ag and HBV DNA detection rate was also higher.Conclusion HBV Per S1-Ag Was a very valuable serum marker in terms of direct HBV replication alone can not HBeAg-positive to determine whether the replication of the virus. Key words: Biological narkers; DNA virus Infections

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Key concepts: HBeAg, Medicine, HBsAg, Hepatitis B virus, Virology, Clinical significance, Antigen, Infection rate