2016Zhongguo jiceng yiyaoRequires access

Evaluation of different doses dezocine combined with propofol intravenous anesthesia for artificial abortion

Miaofang Zhang, Chunli Ying

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Abstract

Objective To evaluate clinical results of different doses of dezocine combined with propofol intravenous anesthesia in abortion. Methods 150 patients with routinely abortion were randomly divided into group A, B, C, at induction the patients were given anesthesia dezocine intravenous doses of 0.025mg/kg, 0.05mg/kg, 0.1mg/kg, 10min after slowly intravenous injection of propofol, the clinical results were compared in three groups of artificial abortion. Results Each time during surgery, mean arterial pressure(MAP), heart rate(HR) and blood pressure pulse saturation(SpO2) indicators in group B were more stable than groups A, C the operations security was higher (tA=6.06, tB=0.88, tC=1.73, PA 0.05, PC>0.05). Dose of propofol, postoperative recovery time of group B [(113.56±18.12)mg, (6.72±1.69)min] were significantly better than those in group A [(150.01±21.45)mg, (10.43±3.38)min], and the differences were statistically significant(t=9.17, 6.94, all P 0.05). The incidence rate of adverse reactions of group B (8.00%) was significantly lower than that in A group(30.00%), and the difference was statistically significant(χ2=2.21, P 0.05). Conclusion Abortion application dose of 0.05mg/kg of dezocine combined with propofol intravenous anesthesia has the best clinical effect, each relatively stable vital signs after surgery, can effectively reduce the dose of propofol, shorten the operation time and postoperative recovery time, and has fewer adverse reactions. Key words: Abortion, induced; Anesthesia; Dezocine; Propofol

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Objective To evaluate clinical results of different doses of dezocine combined with propofol intravenous anesthesia in abortion. Methods 150 patients with routinely abortion were randomly divided into group A, B, C, at induction the patients were given anesthesia dezocine intravenous doses of 0.025mg/kg, 0.05mg/kg, 0.1mg/kg, 10min after slowly intravenous injection of propofol, the clinical results were compared in three groups of artificial abortion. Results Each time during surgery, mean arterial pressure(MAP), heart rate(HR) and blood pressure pulse saturation(SpO2) indicators in group B were more stable than groups A, C the operations security was higher (tA=6.06, tB=0.88, tC=1.73, PA 0.05, PC>0.05). Dose of propofol, postoperative recovery time of group B [(113.56±18.12)mg, (6.72±1.69)min] were significantly better than those in group A [(150.01±21.45)mg, (10.43±3.38)min], and the differences were statistically significant(t=9.17, 6.94, all P 0.05). The incidence rate of adverse reactions of group B (8.00%) was significantly lower than that in A group(30.00%), and the difference was statistically significant(χ2=2.21, P 0.05). Conclusion Abortion application dose of 0.05mg/kg of dezocine combined with propofol intravenous anesthesia has the best clinical effect, each relatively stable vital signs after surgery, can effectively reduce the dose of propofol, shorten the operation time and postoperative recovery time, and has fewer adverse reactions. Key words: Abortion, induced; Anesthesia; Dezocine; Propofol

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Available abstract

Objective To evaluate clinical results of different doses of dezocine combined with propofol intravenous anesthesia in abortion. Methods 150 patients with routinely abortion were randomly divided into group A, B, C, at induction the patients were given anesthesia dezocine intravenous doses of 0.025mg/kg, 0.05mg/kg, 0.1mg/kg, 10min after slowly intravenous injection of propofol, the clinical results were compared in three groups of artificial abortion. Results Each time during surgery, mean arterial pressure(MAP), heart rate(HR) and blood pressure pulse saturation(SpO2) indicators in group B were more stable than groups A, C the operations security was higher (tA=6.06, tB=0.88, tC=1.73, PA 0.05, PC>0.05). Dose of propofol, postoperative recovery time of group B [(113.56±18.12)mg, (6.72±1.69)min] were significantly better than those in group A [(150.01±21.45)mg, (10.43±3.38)min], and the differences were statistically significant(t=9.17, 6.94, all P 0.05). The incidence rate of adverse reactions of group B (8.00%) was significantly lower than that in A group(30.00%), and the difference was statistically significant(χ2=2.21, P 0.05). Conclusion Abortion application dose of 0.05mg/kg of dezocine combined with propofol intravenous anesthesia has the best clinical effect, each relatively stable vital signs after surgery, can effectively reduce the dose of propofol, shorten the operation time and postoperative recovery time, and has fewer adverse reactions. Key words: Abortion, induced; Anesthesia; Dezocine; Propofol

Key concepts: Medicine, Dezocine, Propofol, Anesthesia, Abortion, Blood pressure, Adverse effect, Heart rate

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