The application of dezocine combined with propofol for induced abortion

Objective Comparison of dezocine or fentanyl combined with propofol intravenous anesthesia in artificial abortion of clinical effect and safety.Methods Nighty ASA Ⅰ～Ⅱinduced abortion patients were randomly divided into 3 groups(n=30),Groups Ⅰwas administrated with 5 mg dezocine first,after 10 min with 2 mg/kg propofol,Groups Ⅱ was administrated with 1 μg/kg fentanyl first,after 10 min with 2 mg/kg propofol,Group Ⅲ was administrated with 5 mg dezocine first,after 8 min with 0.5 μg/kg fentanyl,after 10 min with 2 mg/kg propofol.Observed in MAP,HR,SpO2,RR,loss of consciousness and awakening time,Propofol dose,anesthetic effect,adverse reaction and the postoperative pain score.Results All Group was no significant difference in recovery time,the dosage of propofol,the anesthetic effect(P0.05).All group MAP,SPO were lower than those before treatment(P0.05),Group II after administration of SpO2 less than I、Ⅲ group(P 0.05).Group I intraoperative and postoperative adverse reaction the incidence is lower than II、Ⅲ Group(P 0.05),Group Ⅱ after lower abdominal pain VAS score 0 a 1 points less than I、Ⅲ group(P0.05).Conclusion Dezocine have analgesic effect and satisfactory effect for artificial abortion operation anesthesia,compared with fentanyl,do not increase the dosage of propofol,respiratory depression and other adverse reaction is lower,alone or with small dose of fentanyl,reduction of the incidence of postoperative abdominal pain