2013•Chinese Journal of AsthmaRequires access

Role of Th17/IL-17 in the pathogenesis of bronchial asthma

Feifei Chen, Mao Huang

Abstract

Bronchial asthma (asthma) is a chronic inflammatory disease which involvding a variety of inflammatory cells and inflammatory mediators,but the specific pathogenesis is not yet clear.Recent studies have found that Th17 cells and their cytokine IL-17 involved in the genesis and development of asthma,and play an important role in the process.Th17 cells is a novel class of CD4 + T cells,IL-17 is the main cytokines.In this review,we mainly investigate the role of Th17/IL-17 in the pathogenesis of asthma. Key words: Bronchial asthma; Th17 ; Interleukin-17

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Key concepts: Pathogenesis, Medicine, Asthma, Immunology, Cytokine, Disease, Interleukin 17, Inflammation