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2012•Chinese Journal of AsthmaRequires access

Role of interleukin-33 in pathogenesis of bronchial asthma

Rui-bing Zheng, Feng Wu

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Abstract

Interleukin-33 (IL-33) is a novel member of IL-1 cytokine family,which mediates its biological effects as a ligand for ST2. IL-33 induces expression of Th2 cytokines and has a variety of effects on inflammatory cells.Growing evidence suggests that IL-33 plays a crucial role in the pathogenesis of bronchial asthma. As such,it is hoped that IL-33 will be a novel therapeutic target for bronchial asthma. Key words: Interleukin-33 ;  Bronchial asthma ;  Pathogenesis

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What this paper is about

Interleukin-33 (IL-33) is a novel member of IL-1 cytokine family,which mediates its biological effects as a ligand for ST2. IL-33 induces expression of Th2 cytokines and has a variety of effects on inflammatory cells.Growing evidence suggests that IL-33 plays a crucial role in the pathogenesis of bronchial asthma. As such,it is hoped that IL-33 will be a novel therapeutic target for bronchial asthma. Key words: Interleukin-33 ;  Bronchial asthma ;  Pathogenesis

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OpenAlex reports 2 citations for this work. Citation counts describe recorded attention and do not establish research quality.

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Available abstract

Interleukin-33 (IL-33) is a novel member of IL-1 cytokine family,which mediates its biological effects as a ligand for ST2. IL-33 induces expression of Th2 cytokines and has a variety of effects on inflammatory cells.Growing evidence suggests that IL-33 plays a crucial role in the pathogenesis of bronchial asthma. As such,it is hoped that IL-33 will be a novel therapeutic target for bronchial asthma. Key words: Interleukin-33 ;  Bronchial asthma ;  Pathogenesis

Key concepts: Pathogenesis, Medicine, Asthma, Immunology, Cytokine, Interleukin 33, Interleukin, Interleukin 6

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