Clinical observation of BiPAP ventilation in the treatment of chronic obstructive pulmonary disease with respiratory failure

Objective To compare the effect of bi - level positive airway pressure ventilation in chronic obstructive pulmonary disease (COPD) with respiratory failure and the therapeutic effect of conventional method. Methods Ninety patients selected were randomly divided into treatment and control groups,45 cases in each group.The conventional treatment (including anti -infection,expectorant,asthma,symptomatic correction of electrolyte disorders and acid - base imbalance and nutritional support treatment,and when necessary given corticosteroids,etc.) was the same,treatment group were given bi -level positive airway pressure treatment,3 days for a treatment period,patients were observed for 3 days of the signs and symptoms and pH,PCO2,PO2,HR index changes,and with the control group made between the values of blood gas analysis of the statistical analysis.Results Of clinical symptoms in patients treated with BiPAP,signs and blood gas analysis after treatment than before treatment had significantly improved.Compared with the control group,there were significant differences (P ＜ 0.05).Conclusions The effect of BiPAP ventilatory support for treating COPD with respiratory failure is good. Key words: Bi -level positive airway pressure ventilation; Chronic obstructive pulmonary disease; Respiratory failure