Clinical research of carboprost methylate suppository combined with romethamine in the treatment of postpartum hemorrhage in contractions fatigue

Objective To analyze the effect of carboprost methylate suppository combined with romethamine in the treatment of postpartum hemorrhage in contractions fatigue. Methods 120 cases of postpartum hemorrhage contractions fatigue were randomly divided into control group and observation group, 60 cases in each group.The control group was given carboprost methylate suppository treatment, the observation group was given romethamine combined with carboprost methylate suppository.The 2h, 12h postpartum blood loss, clinical treatment effect and adverse reaction were compared between the two groups. Results Compared with the control group, the hemostatic time of the observation group shortened, postpartum haemorrhage amount within 2h and postnatal within 12h blood loss of the observation group were reduced, the differences were statistically significant (t=4.56, 5.92, 6.12, all P<0.05). The total effective rate of the control group was 73.33%, which was significantly lower than 91.67% of the observation group, the difference was statistically significant (χ2=6.12, P<0.05). Compared with the control group, the incidence rates of digestive tract symptoms, disposable blood pressure fluctuations, facial blushing, puerperal infection in the observation group were lower, the differences were statistically significant (χ2=4.71, 4.98, 4.34, 5.43, all P<0.05). Conclusion The clinical effect of carboprost methylate suppository combined with romethamine in the the treatment of contractions fatigue postpartum hemorrhage is remarkable, with less postpartum haemorrhage amount, better treatment effect, low incidence of adverse reactions and higher security. Key words: Uterine inertia; Postpartum hemorrhage; Carboprost methylate suppository; Romethamine