Curative effect comparison of romethamine and carboprost methylate in prevention of postpartum hemorrhage of scar uterus vaginal delivery

Objective To investigate the curative effect comparison of romethamine and carboprost methylate in prevention of postpartum hemorrhage of scar uterus vaginal delivery. Methods 120 women with scar uterus vaginal delivery in our hospital from January 2013 to December 2014 were selected and randomly divided into observation group and control group,60 cases in each group.After delivery of fetus,control group were given with oxytocin intramuscular injection 20 U and carboprost methylate sublingual 1 mg at the same time,observation group were given with oxytocin intramuscular 20 U and romethamine 250 μg injection.The amount of bleeding in 2,24 h after delivery,third stage of labor,incidence rate of postpartum hemorrhage and adverse reaction were compared between two groups of postpartum.Results In observation group,the amount of bleeding in 2,24 h after delivery was(223.62±92.40),(322.08±92.40) ml respectively,less than that in control group[(285.00±120.10),(387.10±127.07) ml] respectively,with significant difference(P0.05).Third stage of labor in observation group[(6.87±1.60) min] was shorter than that in control group[(8.77±2.07) min],with significant difference(P0.05).The incidence rate of postpartum hemorrhage in observation group(3.33%) was lower than that in control group(13.33%),with significant difference(P0.05).There was no statistical difference in the incidence rate of adverse reaction between two groups(P0.05). Conclusion Romethamine prevention of postpartum hemorrhage of scar uterus vaginal delivery is better than carboprost methylate.It is worthy of clinical promotion and application.