Clinical analysis of 60 cases of pulmonary sarcoidosis

Objective To investigate the clinical and pathological features, diagnose and treatment method and prognosis of pulmonary sarcoidosis. Methods Sixty patients diagnosed as pulmonary sarcoidosis by histopathology were selected and the clinical manifestations, laboratory examinations and imaging examinations of them were analyzed retrospectively. Results The average age of all patients was 54.6 years, and there were more female patients than male; the main clinical symptoms included respiratory symptoms and extrapulmonary manifestations; angtiotensin converting enzyme (ACE), blood biochemistry, T-SPOT were helpful for the diagnosis; chest imaging was helpful for early diagnosis, and definite diagnosis depended on histopathological examination, such as lung biopsy, lymph node biopsy, skin biopsy; corticosteroids was the first choice for the treatment of sarcoidosis, followed by methotrexate, with a better prognosis and a few cases of relapse or disease progression. Conclusions The clinical manifestation of pulmonary sarcoidosis is various, so the histopathological examination should be complete as far as possible for definite diagnosis; glucocorticoid is the first choice for the treatment of pulmonary sarcoidosis, and the prognosis is good in most patients. Key words: Pulmonary sarcoidosis; Clinical features; Diagnosis