Clinical analysis of 38 cases with sarcoidosis

Objective To explore the clinical features,diaognosis and therapy of sarcoidosis.Methods Clinical materials of 38 consecutive patients with biopsy-proven sarcoidosis were retrospectively analyzed.Results The average age was 54.6 years,there were more female patients than male.Sarcoidosis had several clinical features,including respiratory system and extropulmonary presentation.X-ray test of chest was the major way to diagnose the disease at early stage.Both the biopsy of lymphonodus of mediastinum through mediastinoscopy and the lung biopsy by video-assisted thoracoscopic surgery were the better methods for the diagnosis of sarcoidosis,and the diagnosis was depended on histopathology.Conclusion The clinical presentation of sarcoidosis is varied and nonspecific.Pathological examination should be made for the prevention of missed diagnosis and misdiagnosis,and glucocorticoid was the effective drug for therapy.