2015•Chin J Gastroesophagol Reflux Dis(Electronic Edition)Requires access
Observation of clinical efficacy of esomeprazole in combination of mosapride in the treatment of reflux esophagitis after resection of cardiac carcinoma
Chun Yang
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Abstract
Objective
To explore the clinical efficacy of esomeprazole in combination of mosapride in the treatment of reflux esophagitis after resection of cardiac carcinoma.
Methods
76 patients with reflux esophagitis after resection of cardiac carcinoma were randomized into two group, treatment group and Control group.The treatment group(n=38)received treatment of esomeprazole plus mosapride, and the control group(n=38)received treatment of mosapride only.Improvements of clinical symptoms and endoscoic pathological changes after 8 weeks were observed.
Results
Clinical efficacy and and endoscope results of treatment group were better than control group, with statistically difference(P<0.05).
Conclusion
Esomeprazole in combination of mosapride shows more significant clinical efficacy then mosapride only in the treatment of reflux esophagitis after resection of cardiac carcinoma, which is worth a clinical promotion.
Key words:
Esophagitis, Peptic; Esomeprazole, cardiac carcinoma