2006Zhongguo jiceng yiyaoRequires access

Relationship between maternal hepatic function and fetal prognosis in intrahepatic cholestasis of pregnancy

富晓敏, 蒋青, 王淑兰, 薛荣丽

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Abstract

目的 探讨妊娠期肝内胆汁淤积症(ICP)孕妇肝功能指标与围生儿预后的关系.方法对166例ICP孕妇肝功能指标及围生儿预后进行回顾性分析.结果孕妇血清转氨酶(ALT,AST)及胆红素(BIL)水平升高者胎儿窘迫及羊水粪染发生率增加,新生儿体重及Apgar评分与胆红素水平有关,通过公式计算可以预测围生儿预后.孕妇胆汁酸(TBA)升高程度与羊水粪染及胎儿窘迫发生率无关.结论 ICP孕妇转氨酶及胆红素水平升高者胎儿预后不佳,必须高度重视,适时剖宫产终止妊娠将明显改善围生儿预后。

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目的 探讨妊娠期肝内胆汁淤积症(ICP)孕妇肝功能指标与围生儿预后的关系.方法对166例ICP孕妇肝功能指标及围生儿预后进行回顾性分析.结果孕妇血清转氨酶(ALT,AST)及胆红素(BIL)水平升高者胎儿窘迫及羊水粪染发生率增加,新生儿体重及Apgar评分与胆红素水平有关,通过公式计算可以预测围生儿预后.孕妇胆汁酸(TBA)升高程度与羊水粪染及胎儿窘迫发生率无关.结论 ICP孕妇转氨酶及胆红素水平升高者胎儿预后不佳,必须高度重视,适时剖宫产终止妊娠将明显改善围生儿预后。

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Available abstract

目的 探讨妊娠期肝内胆汁淤积症(ICP)孕妇肝功能指标与围生儿预后的关系.方法对166例ICP孕妇肝功能指标及围生儿预后进行回顾性分析.结果孕妇血清转氨酶(ALT,AST)及胆红素(BIL)水平升高者胎儿窘迫及羊水粪染发生率增加,新生儿体重及Apgar评分与胆红素水平有关,通过公式计算可以预测围生儿预后.孕妇胆汁酸(TBA)升高程度与羊水粪染及胎儿窘迫发生率无关.结论 ICP孕妇转氨酶及胆红素水平升高者胎儿预后不佳,必须高度重视,适时剖宫产终止妊娠将明显改善围生儿预后。

Key concepts: Medicine, Cholestasis of pregnancy, Cholestasis, Pregnancy, Fetus, Hepatic function, Obstetrics, Gastroenterology

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