Applicion of BiPAP in elderly patients with severe COPD during acute exacerbation period complicated with type II respiratory failure

Objective To investigate the clinical effect of Bi-level positive airway pressure ventilation (BiPAP) on respiratory failure resulted from acute exacerbation period of chronic obstructive pulmonary disease (AECOPD).Methods Fifty elderly patients with acute respiratory failure resulted from AECOPD were choosed in the study.The changes in the artery blood gas( PaO2,SaO2,pH,SaO2 ) and vital signs( RR,HR) were compared before and after the treatment.Results After treatment,the PaO2,SaO2,pH values were higher,and the RR,HR and PaCO2 were lower,there were significant differences (P ＜ 0.01 ).Conclusions BiPAP assisted ventilation is certainly effective in the treatment of COPD combined with type Ⅱ respiratory failure,and has no obvious complications,is worth to be popularized. Key words: Bi-level positive airway pressure ventilation(BiPAP) ;  Chronic obstructive pulmonary disease;  Respiratory failure