Efficacy of BiPAP ventilation in II type respiratory failure patients with acute exacerbation of chronic obstructive pulmonary disease

Objective To observe the efficacy of BiPAP ventilation in Ⅱ type respiratory failure patients with acute exacerbation of chronic obstructive pulmonary disease(AECOPD).Methods Fifty-six cases of acute exacerbation of COPD with Ⅱ type respiratory failure were treated with BiPAP ventilation via face/nasal mask.The clinical manifestations,respiratory rate(RR),heart rate(HR),arterial blood gases(ABG),scale for accessory muscle use,dyspnea score and rapid shallow breathing index(RSBI) were compared before treatment,after treatment of 2 hours,6 hours,24 hours,and 72 hours.Results ABG,RR,HR and scale for accessory muscle use were improved rapidly at the first 2h in patients,and there was significant difference between before and after ventilations(P0.05).Conclusion BiPAP ventilation can rapidly relieve respiratory muscular fatigue and improve gas exchange.It shows effective in treating AECOPD with Ⅱ type respiratory failure.