Clinical distribution and drug resistance of Acinetobacter baumannii

OBJECTIVE To study the changing trends of drug resistance of Acinetobacter baumannii isolates. METHODS The bacterial susceptibility results of 1 967 isolates of A.baumannii obtained from clinical patients in the Zhongshan Hospital of Xiamen University between 2005 and 2009 were retrospectively analyzed. RESULTS The isolating rate of A.baumannii was increasing year-by-year from 110 in 2005 to 1040 in 2009,the highest appearing rate was the sputum,up to 87.5%.The resistant rates of A.baumannii to antibacterial drugs were increasing year by year.The resistant rates to gentamicin,levofloxacin and imipenem were increasing from 38.2%,17.3% and 2.7% to 68.9%、67.0% and 68.8%,respectively.The resistant rates to cefoperazone/sulbactam,ampicillin/sulbactam,piperacillin/sulbactam and polymyxin B.were low. CONCLUSIONS The isolation rate of ABA from clinics is increased year by year,and the resistance gradually becomes serious.