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2013•Prevention and Treatment of Cardio-Cerebral-Vascular DiseaseRequires access

Effects of Percutaneous Cornary Intervention on Inflammatory Factors and Platelet Activation in Patients with Acute Coronary Syndrome

XU Hai-bin

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Abstract

Objective To discuss the effects of percutaneous cornary intervention(PCI) on inflammatory factors and platelet activation in patients with acute coronary syndrome(ACS).Methods Inflammatory factors(IL-6 and Hs-CRP) and platelet activation(CD62p and CD63) were detected in 60 paitients who accepted PCI with ACS before and after the operation,then the changes were analyzed.Results IL-6,Hs-CRP,CD62p,and CD63 after PCI were significantly higher than before(P0.01),and 24 hours after PCI were significantly higher than the other times(P0.01),decreased at 72 hours after PCI,and down to the preoperative level at 96 hours after PCI.Conclusions PCI can lead to platelet activation and expression of inflammatory cytokines increased because of vascular endothelial injury,and increase the thrombosis incidence and RS.

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What this paper is about

Objective To discuss the effects of percutaneous cornary intervention(PCI) on inflammatory factors and platelet activation in patients with acute coronary syndrome(ACS).Methods Inflammatory factors(IL-6 and Hs-CRP) and platelet activation(CD62p and CD63) were detected in 60 paitients who accepted PCI with ACS before and after the operation,then the changes were analyzed.Results IL-6,Hs-CRP,CD62p,and CD63 after PCI were significantly higher than before(P0.01),and 24 hours after PCI were significantly higher than the other times(P0.01),decreased at 72 hours after PCI,and down to the preoperative level at 96 hours after PCI.Conclusions PCI can lead to platelet activation and expression of inflammatory cytokines increased because of vascular endothelial injury,and increase the thrombosis incidence and RS.

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Available abstract

Objective To discuss the effects of percutaneous cornary intervention(PCI) on inflammatory factors and platelet activation in patients with acute coronary syndrome(ACS).Methods Inflammatory factors(IL-6 and Hs-CRP) and platelet activation(CD62p and CD63) were detected in 60 paitients who accepted PCI with ACS before and after the operation,then the changes were analyzed.Results IL-6,Hs-CRP,CD62p,and CD63 after PCI were significantly higher than before(P0.01),and 24 hours after PCI were significantly higher than the other times(P0.01),decreased at 72 hours after PCI,and down to the preoperative level at 96 hours after PCI.Conclusions PCI can lead to platelet activation and expression of inflammatory cytokines increased because of vascular endothelial injury,and increase the thrombosis incidence and RS.

Key concepts: Conventional PCI, Medicine, Percutaneous coronary intervention, Acute coronary syndrome, Platelet activation, Cardiology, Internal medicine, Platelet

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Effects of Percutaneous Cornary Intervention on Inflammatory Factors and Platelet Activation in Patients with Acute Coronary Syndrome — Research Paper | ScholarLens