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2009•Chinese Heart JournalRequires access

Variance of IL-6,IL-10,and MMP-1 in patients with acute coronary syndrome after percutaneous coronary intervention and the interrelation of cytokines and restenosis

Xianming Wu

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Abstract

AIM: To detect the variance of IL-6,IL-10,and MMP-1 in patients with acute coronary syndrome(ACS) after percutaneous coronary intervention(PCI) and the interrelation of cytokines and restenosis.METHODS: Serum concentrations of IL-6,IL-10 and MMP-1 were measured in 64 patients with ACS.Pre-and post-PCI was done by enzyme-linked immunosorbent assay(ELISA),and patients were followed-up after 6 months.RESULTS: Serum concentrations of IL-6 and MMP-1 significantly increased after PCI.When comparing the restenosis group to the no-restenosis qroup,they are different both pre-and post-PCI.CONCLUSION: Serum inflammatory levels were augmented by PCI and may predict restenosis.

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What this paper is about

AIM: To detect the variance of IL-6,IL-10,and MMP-1 in patients with acute coronary syndrome(ACS) after percutaneous coronary intervention(PCI) and the interrelation of cytokines and restenosis.METHODS: Serum concentrations of IL-6,IL-10 and MMP-1 were measured in 64 patients with ACS.Pre-and post-PCI was done by enzyme-linked immunosorbent assay(ELISA),and patients were followed-up after 6 months.RESULTS: Serum concentrations of IL-6 and MMP-1 significantly increased after PCI.When comparing the restenosis group to the no-restenosis qroup,they are different both pre-and post-PCI.CONCLUSION: Serum inflammatory levels were augmented by PCI and may predict restenosis.

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Available abstract

AIM: To detect the variance of IL-6,IL-10,and MMP-1 in patients with acute coronary syndrome(ACS) after percutaneous coronary intervention(PCI) and the interrelation of cytokines and restenosis.METHODS: Serum concentrations of IL-6,IL-10 and MMP-1 were measured in 64 patients with ACS.Pre-and post-PCI was done by enzyme-linked immunosorbent assay(ELISA),and patients were followed-up after 6 months.RESULTS: Serum concentrations of IL-6 and MMP-1 significantly increased after PCI.When comparing the restenosis group to the no-restenosis qroup,they are different both pre-and post-PCI.CONCLUSION: Serum inflammatory levels were augmented by PCI and may predict restenosis.

Key concepts: Conventional PCI, Restenosis, Percutaneous coronary intervention, Medicine, Internal medicine, Acute coronary syndrome, Cardiology, Myocardial infarction

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Variance of IL-6,IL-10,and MMP-1 in patients with acute coronary syndrome after percutaneous coronary intervention and the interrelation of cytokines and restenosis — Research Paper | ScholarLens