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2004•Zhongguo yaofangRequires access

Fentanyl-propofol and Midazolam-propofol Used in Gastroscopy for Aged-patients

Lu H

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Abstract

OBJECTIVE:To evaluate the sedative and analgesic effects and safty of fentanyl-propofol and midazolam-propofol by intravenous injection in gastroscopy for aged-patients.METHODS:128aged-patients were randomly divided into3groups:fentanyl-propofol group(groupⅠ),midazolam-propofol group(groupⅡ)and ordinary gastroscopy group(groupⅢ).The effects of sedation and analgesia and the variation of SBP,HR and SDNN were observed.RESULTS:Patients in groupⅠandⅡfelt much less discomfortable than those in groupⅢ(P0.05)and also the examination time in groupⅠandⅡwas shorter than that in groupⅢ.In groupⅠandⅡ,the SBP,HR and SDNN during examination only slightly decreased,all in normal degrees,compared with those before gastroscopy,but in groupⅢ,the SBP and HR during examination increased sigˉnificantly and the SDNN decreased remarkablely(P0.05).CONCLUSION:Using fentanyl-propofol or midazolam-propofol by intravenous injection can make gastroscopy more comfortable,more effective and safer for aged-patients.

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OBJECTIVE:To evaluate the sedative and analgesic effects and safty of fentanyl-propofol and midazolam-propofol by intravenous injection in gastroscopy for aged-patients.METHODS:128aged-patients were randomly divided into3groups:fentanyl-propofol group(groupⅠ),midazolam-propofol group(groupⅡ)and ordinary gastroscopy group(groupⅢ).The effects of sedation and analgesia and the variation of SBP,HR and SDNN were observed.RESULTS:Patients in groupⅠandⅡfelt much less discomfortable than those in groupⅢ(P0.05)and also the examination time in groupⅠandⅡwas shorter than that in groupⅢ.In groupⅠandⅡ,the SBP,HR and SDNN during examination only slightly decreased,all in normal degrees,compared with those before gastroscopy,but in groupⅢ,the SBP and HR during examination increased sigˉnificantly and the SDNN decreased remarkablely(P0.05).CONCLUSION:Using fentanyl-propofol or midazolam-propofol by intravenous injection can make gastroscopy more comfortable,more effective and safer for aged-patients.

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Available abstract

OBJECTIVE:To evaluate the sedative and analgesic effects and safty of fentanyl-propofol and midazolam-propofol by intravenous injection in gastroscopy for aged-patients.METHODS:128aged-patients were randomly divided into3groups:fentanyl-propofol group(groupⅠ),midazolam-propofol group(groupⅡ)and ordinary gastroscopy group(groupⅢ).The effects of sedation and analgesia and the variation of SBP,HR and SDNN were observed.RESULTS:Patients in groupⅠandⅡfelt much less discomfortable than those in groupⅢ(P0.05)and also the examination time in groupⅠandⅡwas shorter than that in groupⅢ.In groupⅠandⅡ,the SBP,HR and SDNN during examination only slightly decreased,all in normal degrees,compared with those before gastroscopy,but in groupⅢ,the SBP and HR during examination increased sigˉnificantly and the SDNN decreased remarkablely(P0.05).CONCLUSION:Using fentanyl-propofol or midazolam-propofol by intravenous injection can make gastroscopy more comfortable,more effective and safer for aged-patients.

Key concepts: Propofol, Midazolam, Fentanyl, Medicine, Anesthesia, Sedation, Sedative, Analgesic

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