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2014•Medical Journal of Trauma and DisabilityRequires access

Differential Diagnosis Value of CD117,CD13 and CD33in Acute Myeloid Leukemia

Dongfang Guo

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Abstract

Objectives: To study the differential diagnosis value of CD117 、CD13 and CD33 in acute myeloid leukemia. Methods: The peripheral blood and bone marrow of 510 cases with acute myeloid leukemia was analyzed by flow cytometry. Results: In acute myeloid leukemia,the percent of expression in CD117,CD13 and CD33 was 91. 9% 、91. 6% and 94. 4%. These were significantly higher compared with acute lymphoblastic leukemia( P < 0. 01); Conclusion: CD117,CD13 and CD33 might be significant in differential diagnosis between acute myeloid leukemia and acute lymphoblastic leukemia.

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What this paper is about

Objectives: To study the differential diagnosis value of CD117 、CD13 and CD33 in acute myeloid leukemia. Methods: The peripheral blood and bone marrow of 510 cases with acute myeloid leukemia was analyzed by flow cytometry. Results: In acute myeloid leukemia,the percent of expression in CD117,CD13 and CD33 was 91. 9% 、91. 6% and 94. 4%. These were significantly higher compared with acute lymphoblastic leukemia( P < 0. 01); Conclusion: CD117,CD13 and CD33 might be significant in differential diagnosis between acute myeloid leukemia and acute lymphoblastic leukemia.

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Available abstract

Objectives: To study the differential diagnosis value of CD117 、CD13 and CD33 in acute myeloid leukemia. Methods: The peripheral blood and bone marrow of 510 cases with acute myeloid leukemia was analyzed by flow cytometry. Results: In acute myeloid leukemia,the percent of expression in CD117,CD13 and CD33 was 91. 9% 、91. 6% and 94. 4%. These were significantly higher compared with acute lymphoblastic leukemia( P < 0. 01); Conclusion: CD117,CD13 and CD33 might be significant in differential diagnosis between acute myeloid leukemia and acute lymphoblastic leukemia.

Key concepts: CD33, Myeloid leukemia, CD117, Medicine, Acute leukemia, Myeloid, Leukemia, Bone marrow

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