Comparation of pathological results of conization and cervix biopsy

Objective To investigate the differences of pathological results between multiple sites biopsy and cold knife cervical conization,and to evaluate the accurancy of cervix biopsy,and the diagnostic and therapeutic value of cervical conization for the patients with cervical intraepithelial neoplasia(CIN).Methods 96 patients with cervical intraepithelial neoplasia were performed cold knife conization,and the results of the two methods were compared.Results On the premise that the coordinate pathological levels were the same,54 cases were accordant with cervix biopsy results after conization,while 42 cases were not.Among the 42 cases,10 patients′(10/96,10.4%) diagnostic results after conization were more serious than that of biopsy,and 32 patients′(32/56,76.2%) were milder.Conclusion It is insufficient to diagnose and treat the patients with CIN only based on cervix biopsy.Cervical conization plays an important role in diagnosing and treating patients,especially those with moderate and sever cervical intraepithelial neoplasia.