Study on cervical cold knife conization in diagnosis and treatment of cervical lesions

Objective To analyze the effect and significance of cervical conization in diagnosis and treatment of cervical intraepithelial neoplasia(CIN).Methods The data of 49 patients with CIN treated in this department during August 2006 to October 2010 were retrospectively analyzed.Thirty six patients with grades CIN Ⅱ and Ⅲ were taken with colposcopy and cervical biopsy under multi-cone biopsy or cervical conization,and self-control method was applied for pathological tissue diagnosis.Results The coincidence rate of thirty six patients with cervical multi-cone biopsy and pathological report reached 61.11%(22/36).Postoperative bleeding after conization was seen in 3 cases,and they were cured by coagulation hemostasis or local pressing.They had been followed up for 3 to 12 months,no cytological abnormalities had been found.Conclusion Conization can effectively remedy the defects of colposcopic biopsy in diagnosis,and it may greatly improve the accuracy of diagnosis and raise the effectiveness of treatment,it is an effective diagnostic and therapeutic method,hence it is worthy to be recommended for clinical application.