Evaluation of effect of cervical conization on cervical intraepithelial neoplasia III

Objective:To explore the value of cervical conization in the diagnosis and therapy of patients with cervical intraepithelial neoplasia Ⅲ (CINⅢ).Methods:Clinical data of 255 cases with CINⅢ from 2003 to 2007 were analysed retrospectively,a self-controlled study was conducted,the pathologic results of cervical conization and colposcopic multi-point biopsy were compared.Results:The pathologic coincidence rate of cervical conization and colposcopic multi-point biopsy was 74.56%.32 cases (12.70%) of microinvasive cancer and 5 cases (1.98%) of invasive cancer of cervix were missed.189 cases (75.00%) after cervical conization were followed up for 16.4 months (average time),no cytological abnormality was detected,and 3 cases were pregnant and delivered.Conclusion:Cervical conization plays an important role in the diagnosis and therapy of patients with CINⅢ,which can't be instead of colposcopic multi-point biopsy.Cervical conization is the first choice for the young patients with CINⅢ who demand retention of reproductive function.