2012Laboratory Medicine and ClinicRequires access

Clinical application of joint detection of two methods about Treponema pallidum antibody

Min Luo

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Abstract

Objective To study the importance and necessity that syphilis Tolulized red unheated serum test(TRUST)and Treponema pallidum Gelati particle agglutinatio Test(TPPA) for Treponema pallidum antibody simultaneously.Methods The serum Treponema pallidum antibody of the 1 994 clinical blood transfusion,surgery and dermatology patients were tested simultaneously by TRUST and TPPA,and the positive samples were retested for titration.Results 22 cases were positive,positive rate was 1.1% by TRUST.40 cases was positive,the positive rate was 2.0% by TPPA.While 18 cases were positive,the positive rate was 0.9% in both tests.Conclusion Early diagnosis can avoid unnecessary patient disputes,TPPA should be used to detect treponema pallidum antibody for the screening of blood donor and diagnosis of suspected infection,the positive samples were retested by TRUST.Not only to improve the detection rate,but also to reduce the false positive rate.

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Objective To study the importance and necessity that syphilis Tolulized red unheated serum test(TRUST)and Treponema pallidum Gelati particle agglutinatio Test(TPPA) for Treponema pallidum antibody simultaneously.Methods The serum Treponema pallidum antibody of the 1 994 clinical blood transfusion,surgery and dermatology patients were tested simultaneously by TRUST and TPPA,and the positive samples were retested for titration.Results 22 cases were positive,positive rate was 1.1% by TRUST.40 cases was positive,the positive rate was 2.0% by TPPA.While 18 cases were positive,the positive rate was 0.9% in both tests.Conclusion Early diagnosis can avoid unnecessary patient disputes,TPPA should be used to detect treponema pallidum antibody for the screening of blood donor and diagnosis of suspected infection,the positive samples were retested by TRUST.Not only to improve the detection rate,but also to reduce the false positive rate.

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Available abstract

Objective To study the importance and necessity that syphilis Tolulized red unheated serum test(TRUST)and Treponema pallidum Gelati particle agglutinatio Test(TPPA) for Treponema pallidum antibody simultaneously.Methods The serum Treponema pallidum antibody of the 1 994 clinical blood transfusion,surgery and dermatology patients were tested simultaneously by TRUST and TPPA,and the positive samples were retested for titration.Results 22 cases were positive,positive rate was 1.1% by TRUST.40 cases was positive,the positive rate was 2.0% by TPPA.While 18 cases were positive,the positive rate was 0.9% in both tests.Conclusion Early diagnosis can avoid unnecessary patient disputes,TPPA should be used to detect treponema pallidum antibody for the screening of blood donor and diagnosis of suspected infection,the positive samples were retested by TRUST.Not only to improve the detection rate,but also to reduce the false positive rate.

Key concepts: Treponema, Syphilis, Medicine, Antibody, False positive rate, Internal medicine, Immunology, Statistics

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