THE DRUG TOLERANCE ANALYSIS OF 286 STRAINS STAPHYLOCOCCUS

[Objective]To understand the distribution of staphylococcus and it's drug resistance in antimicrobial drugs,to provide clinical referance for drug selection.[Methods]286 strains staphylococcus were identified by 32 type VITEK in our affiliated hospital,susceptibility test was performed by(K-B)method,with the distinguishing standard according to NCCLS 2002.[Results]286 strains staphylococcus were separated.Among them,there were 66 strains staphylococcus aureus,21 strains of which were meticillin-resistant staphylococcus(MRSA)and accounted for 31.8%,Coagulase-negative were 220 strains staphylococeus,186 strains of which were meticillin-resistant coagurase-negative staphylococcus and accounted for 84.5%;MRSA and MRCNS in drug tolerance rate were high to most of antimicrobial agents except Vancomycin and Teicoplanin.The resistance rate of MSS to Penicillin,Ampicillin,Clarithromycin and Erythromycin were high(51.1%-88.9%),while that to the rest antimicrobial agents were low.[Conclusions]The drug tolerance rate of staphylococous increases gradually,physicians should select antibiotic drugs according to drug sensitivity.