Identification and Antibiotic Resistance of Clinical Isolated Staphylococcus

OBJECTIVE To investigate the classification,distribution and antibiotic resistance of clinical isolated Staphylococcus.METHODS To retrospectively analyze the pathogens and the results of drug susceptibility tests of clinical isolated Staphylococcus during from 2001 to 2004.RESULTS Totally 1446 strains of the clinical isolates were isolated in 4 years.From them 297 strains(11 species) were the Staphylococcus spp.The first five species of Staphylococcus were S.aureus(40.7%),S.epidermidis(29.6%),S.haemolyticus(8.0%),S.saprophyticus subsp saprophyticus(4.7%),and S.hominis(4.3%);MRSA and MRCNS were accounted for 67.8% and 63.6%,respectively;the resistance rate of meticillin-resistant Staphylococcus(MRS) to antibiotic was higher than 55% except for that to rifampicin and chloramphenicol was lower than 38%.They were diversified resistance.There were better anti-bacterium activation of meticillin sensitive Staphylococcus(MSS) to antibiotic except for that the resistance rate to penicillin,macrolides and trimethoprim/sulfamesoxazole was higher than 40%.No resistance to vancomycin among the strains of Staphylococcus was found.CONCLUSIONS Identification of Staphylococcus spp and detection of MRS must be strengthened.Using antimicrobial agents rationally is very important on the basis of antimicrobial susceptibility test.