The distribution and resistance analysis of pathogens isolated from 1368 blood samples

Objective To investigate the positive rate,bacteria distribution and drug resistance in blood culture from 2001 to 2006 in our hospital.Methods Blood samples were incubated by automated blood culture analyzer and examined by automated microbial analyzer.Results Of 1 368 blood samples,141(10.3%)samples were positive,which contain 80(56.7%)strains of gram-negative bacteria,46(32.6%)strains of gram-positive bacteria and 12(8.5%)strains of fungus.The resistance rates of Escherichia coli and Klebsiella Pneumoniae to Amppicillin were 92.7% and 92.3% respectively,which were higher than other bacteria's.Among the gram-positive strains,all Staphylococcus aureus and coagulase negative Staphylococci were resistant to Penicillin;Enterococcus also showed resistance to common antibiotics,while Staphylococci strains were sensitive to Vancomycin.However,9.1% of Enterococcus strains showed intermediate resistance to Vancomycin.Conclusion Bacteria isolated from blood culture in our hospital distributed widely.Escherichia coli and Staphylococci were the main pathogens of bacteremia in recent years.It was indicated that the majority of pathogens were severely resistant to many kinds of antibiotics.The laboratory analysis of microbiology should be reported timely and truly to provide information for selecting antibiotics correctly and efficiently.