Effects of applying moxibustion at Zusanli and Guanyuan acupoints on rats' exercise endurance and an ti-oxidant injury of kidney tissue

Objective:To discuss the effects of applying moxibustion at zusanl(iST36)and guanyuan(RN4)acupoints on exercise endurance,blood biochemical indices,and free radicals metablolism of kidney tissue on the basis of establishing long-term incremental treadmill exercise and exhaustive swimming trainings rats models.Method:A total of 30 rats in this experiment were randomly divided into sedentary control group(n=10),training group(n=10),training plus moxibustion group(n=10).And then the exhaustive swimming time were measured in training group and training plus moxibustion group,to obtain those indices of hemoglobin(Hb),blood lactale(Bla),serum creatine kinase(CK),serum blood urea nitrogen(BUN),kidney malondialdehyde(MDA),glutathioc peroxidase(GSH-Px) and superoxide dismutase(SOD).Result:In training plus moxibustion group the exhaustive swimming time extended obviously;compared with sedentary control group in normal training group,plasma Hb decreased significantly(P0.05),plasma Bla,serum CK,serum BUN,MDA increased significantly(P0.05),activities of GSH-Px and SOD decreased significantly(P0.05);compared with training group in training plus moxibustion group,plasma Hb increased obviously(P0.05),plasma Bla,serum CK,serum BUN decreased obviously(P0.05),the content of MDA decreased significantly(P0.05),the activities of GSH-Px and SOD increased significantly(P0.05);compared with sedentary control group in training plus moxibustion group,the plasma Hb increased relatively,but without significant difference(P0.05),plasma Bla increased significantly(P0.05),serum CK,serum BUN increased significantly(P0.05),the content of MDA increased relatively and GSH-Px was lower,but without significant difference(P0.05),activity of SOD increased significantly(P0.05).Conclusion:Moxibustion at zusanli(ST36) and guanyuan(RN4) acupoints can enhance organism hematopoietic function and circulatory system function,promote the regeneration and synthesis of Hb in organism,reduce Bla accumulation,inhibit CK overflowed in muscle cells,decreased serum BUN content and speed up the removal of free radicals in kidney tissue significantly,thereby strengthen the body's resistance to fatigue and enhance the exercise endurance of organism.