Impact of oyster extracts on endurance exercise, skeletal muscle free radicals, and energy metabolism among rats

OBJECTIVE Based on the long-term incremental treadmill exercise and exhaustive swimming training model, this paper aims to discuss the effects of oyster extracts on endurance exercise, skeletal muscle free radicals, and energy metabolism among rats. METHODS 50 rats in this experiment were randomly divided into sedentary control group (Group A, n = 10), training group (Group B, n = 20), drug-given group (Group C, n = 20). In the last training, group B and group C were fur- ther divided into two subgroups: normal training group (Group B1 and Group C1) and increased exhaustive exercise group (Group B2 and Group C2), with 10 rats respectively. The rats in group C were given oyster extracts with the dose of 15 g / kg / d, otherwise, group A and group B were given the same amount physiological saline solution. And then the exhaustive swim- ming time were detected in group B2 and C2 so as to get the those indices of Hb, LD, serum CK, serum BUN, skeletal mus- cle MDA, GSH-Px, SOD, LDH, MDH. RESULTS The exhaustive time among rats in drug-given group C2 was obviously extended; when compared normal training group B1 with sedentary control group A, MDA, LDH, MDH in the quadriceps femoris were significantly increased (P﹤0.05), GSH-Px, SOD activities were significantly decreased; compared drug-given group C1 with training group B1, together with drug-given group C2 with training group B2, the content of MDA in the quadri- ceps femoris was significantly decreased (P ﹤ 0.05) , GSH-Px, SOD, LDH, MDH activities were significantly increased. CONCLUSION Increasing oyster extracts can enhance organism hematopoietic function and circulatory system functions, im- prove antioxidant defense capacities of skeletal muscle, speed up the clearance of free radicals, and strengthen organism syn- thetic capacities in oxygen and anoxic state so as to increase the anti-fatigue capacities and empowerment of organisms in the movement.