2008•Medical Journal of Chinese People's HealthRequires access

Comparative study of Quetiapine and haloperidol in the treatment of schizophrenia

Zhangshun Tu

Abstract

Objective:To explore the efficacy and safety of quetiapine and haloperidol in treatment of schizophrenia.Methods:93 cases of schizophrenia patients were randomly divided into two groups,quetiapine group(n=47) and haloperidol group(n=46),All cases were treated for 6 weeks.Clinical efficacy and drug side effects were evaluated Using the PANSS Scale and TESS Scale.Results: Excellence and remission rate in quetiapine group was 63.8% and 87.2% respectively,and less Extrapyramidal reactions than another group.Conclusions: Quetiapine with small-dose haloperidol effective in the treatment of acute schizophrenia,fewer adverse effects.

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Key concepts: Quetiapine, Haloperidol, Extrapyramidal symptoms, Schizophrenia (object-oriented programming), Medicine, Adverse effect, Positive and Negative Syndrome Scale, Psychology