2008•Chinese Journal of Hospital PharmacyRequires access

Clinical effect of basic fibroblast growth factor on the healing of the skin wound

LI Zhen-yu

Abstract

OBJECTIVE To investigate the clinical effect of basic fibroblast growth factor(bFGF) on the skin wound.METHODS The trial group of 23 patients′ wound was treated with BFGF.At the same time the control group of 25 patients′ wound was treated with the routine way.The results of the healing time,wound-healing rate and the mature degree of granulation tissues was compared.RESULTS There was statistic significance of trial group's to control group in terms of the healing time(P0.05).After the 7th days,there was no statistic significance in terms of the wound-healing rate and the mature degree of granulation tissues.After the 14th and 21the days,there was statistic significance on the two aspects.CONCLUSION The bFGF can shorten the healing time,increase the wound-hearing rate and promote the growth of granulation tissues.

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Key concepts: Basic fibroblast growth factor, Granulation tissue, Wound healing, Medicine, Fibroblast, Surgery, Growth factor, Internal medicine