2003•Heilongjiang Medical JournalRequires access

Study of Basic Fibroblast Growth Factor Improving in Skin Wound Healing

BI Guo-hua

Abstract

Objective To observe the effect of basic fibroblast growth factor (bFGF) on wound healing. Methods The back of mouse was made sterilized wound compared with taking knife wound as model. The wound of the experimental group was controlled with bFGF solution. Whereas the wounds of the control group were covered with bFGF solution. Two froups received the same treatment once a day. The wound tissue were selected and the histology was observed. Results The wound area reduced obviously in treatment group. Fibroblast cells had flourish growth. The quality of capillary vessel and basic fibroblastic group in treatment was manifold than that in control group. Conclusion bFGF could promote the growth of gradulation tissue and had strong promotion on the wound healing.

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Key concepts: Basic fibroblast growth factor, Medicine, Wound healing, Fibroblast, Fibroblast growth factor, Growth factor, Surgery, Internal medicine