2011Laboratory Medicine and ClinicRequires access

Evaluation on alarm prompt function of Sysmex XE-2100 analyzer in detecting abnormal cells of peripheral blood in children

Han Jing-jin

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Abstract

Objective To appraise the alarm prompt function of the Sysmex XE-2100 analyzer to detect abnormal cells in peripheral blood of children.Methods To appraise the reliability of alarm prompt function of the Sysmex XE-2100 analyzer for analyzing abnormal cells in peripheral blood of children,804 samples were examined repeatedly by he Sysmex XE-2100 analyzer and microscope measurement,and a statistical comparison was also made.Results The sensitivity and specificity of the alarming system for abnormal cells were 100% and 69.80%,respectively.The positive predictive value was 54.10%,and the negative predictive value was 100%.The efficiency rate was 77.74%,the false positive rate was 45.90%.Conclusion The Sysmex XE-2100 analyzer has a good sensitivity in analyzing abnormal cells of peripheral blood of children,but its false positive rate is also high,so those samples with abnormal alarm information need to be ascertained by smear for microscope test.

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What this paper is about

Objective To appraise the alarm prompt function of the Sysmex XE-2100 analyzer to detect abnormal cells in peripheral blood of children.Methods To appraise the reliability of alarm prompt function of the Sysmex XE-2100 analyzer for analyzing abnormal cells in peripheral blood of children,804 samples were examined repeatedly by he Sysmex XE-2100 analyzer and microscope measurement,and a statistical comparison was also made.Results The sensitivity and specificity of the alarming system for abnormal cells were 100% and 69.80%,respectively.The positive predictive value was 54.10%,and the negative predictive value was 100%.The efficiency rate was 77.74%,the false positive rate was 45.90%.Conclusion The Sysmex XE-2100 analyzer has a good sensitivity in analyzing abnormal cells of peripheral blood of children,but its false positive rate is also high,so those samples with abnormal alarm information need to be ascertained by smear for microscope test.

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Available abstract

Objective To appraise the alarm prompt function of the Sysmex XE-2100 analyzer to detect abnormal cells in peripheral blood of children.Methods To appraise the reliability of alarm prompt function of the Sysmex XE-2100 analyzer for analyzing abnormal cells in peripheral blood of children,804 samples were examined repeatedly by he Sysmex XE-2100 analyzer and microscope measurement,and a statistical comparison was also made.Results The sensitivity and specificity of the alarming system for abnormal cells were 100% and 69.80%,respectively.The positive predictive value was 54.10%,and the negative predictive value was 100%.The efficiency rate was 77.74%,the false positive rate was 45.90%.Conclusion The Sysmex XE-2100 analyzer has a good sensitivity in analyzing abnormal cells of peripheral blood of children,but its false positive rate is also high,so those samples with abnormal alarm information need to be ascertained by smear for microscope test.

Key concepts: Peripheral blood, Spectrum analyzer, Medicine, False positive rate, ALARM, Pathology, Predictive value, Immunology

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