Evaluation and analysis functions of Sysmex XE-2100 automated blood cell analyzer for warning abnormal blood cell morphology

Objective To appraise the warning function of the Sysmex XE-2100 analyzer for abnormal cells.Methods 855 samples were examined repeatedly by microscope measurement for researching it′s application in analyzing of the abnormal white blood cells and alarms capability of detection abnormality.Results Comparing with microscopic examination,analyzer warning on low PLT had good accordance,Kappa value was 0.97,U=16.90,P0.01.Warning on Left Shift had common accordance,Kappa value was 0.68,U=9.43,P0.01.Warnings on Immature Gran,Atypical Lymph,Blasts,NRBC,PLT Clumps had poor accordance,Kappa value were 0.35,0.31,0.27,0.28 and 0.25 respectively,U value were 7.15,4.89,4.66,4.17 and 4.55 respectively,P0.01.The criteria showed sensitivity was 95.70%,specificity was 81.16% and the accuracy was 85.67%.Conclusion The blood analyzer′s alarm message provides warning and screening roles,may reduce the labor intensity,raises the working efficiency,but cannot replace the microscopy completely.It is necessary to analyze generally for providing comprehensive,accurate and reliable survey report.