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The Expression of IL-17 Correlates with Angiogenesis in Gastric Cancer Tissues

Dong Guang-long

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Abstract

To investigate the potential relationship between IL-17 expression and angiogenesis in human gastric cancer,immunohistochemistry was performed to examine the expression of IL-17 and CD34 in 30 paraffin-embedded gastric cancer tissues.The results show that most of the IL-17-positive cells exhibited the lymphocyte-like feature and the number correlated with the microvessel density(r=0.642,P0.001).In conclusion,there is a positive correlation between IL-17 expression and the microvessel density and IL-17 may contribute to angiogenesis in gastric cancer.

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What this paper is about

To investigate the potential relationship between IL-17 expression and angiogenesis in human gastric cancer,immunohistochemistry was performed to examine the expression of IL-17 and CD34 in 30 paraffin-embedded gastric cancer tissues.The results show that most of the IL-17-positive cells exhibited the lymphocyte-like feature and the number correlated with the microvessel density(r=0.642,P0.001).In conclusion,there is a positive correlation between IL-17 expression and the microvessel density and IL-17 may contribute to angiogenesis in gastric cancer.

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Available abstract

To investigate the potential relationship between IL-17 expression and angiogenesis in human gastric cancer,immunohistochemistry was performed to examine the expression of IL-17 and CD34 in 30 paraffin-embedded gastric cancer tissues.The results show that most of the IL-17-positive cells exhibited the lymphocyte-like feature and the number correlated with the microvessel density(r=0.642,P0.001).In conclusion,there is a positive correlation between IL-17 expression and the microvessel density and IL-17 may contribute to angiogenesis in gastric cancer.

Key concepts: Angiogenesis, Immunohistochemistry, CD34, Cancer, Microvessel, Pathology, Medicine, Neovascularization

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