Analysis of Drug Resistance of Common Clinical Pathogens in 2005

Objective:To investigate the drug resistance of common clinical pathogens separated in clinical microbiology laboratory in West China Hospital in 2005,to provide basis for clinical infectious diseases diagnosis and therapy.Method:Strains were identified using the MicroScan WalkAway40.Susceptibility tests used microdilution broth method.Result:Among clinical common pathogens,the predominant strains was also gram-negative,the first was Pseudomonas aeruginnosa,Escherichia coli and Staphylococcus aureus.Drug resistance of common antimicrobial agents to these pathogens was high.Resistance of ampicillin to Escherichia coli and Enterbanter cloacae was more than 90%.Among gram-negative bacteria which was except for Strenotrophomonas maltrophlilia,the drug resistance of imipenem was the lowest and the next low was amikacin.Resistance of ampicillin to Staphylococcus aureus,Staphylococccus epiderimidis,Staphylococcus haemolytic and Staphylococcus hominis was more high than last years.Resistance of vancomycin to Staphylococcus aureus and Staphylococccus eoiderimidis was 0.There was no vancomycin resistant Staphylococcus strains in the hospital.Conclusion:Among clinical common pathogens,the predominant strains was gram-negative and their resistant rate was high.Among gram-negative bacteria which was except for Strenotrophomonas maltrophlilia,the drug resistance of imipenem was the lowest.Resistance of ampicillin to Staphylococcus aureus,Staphylococccus epiderimidis Staphylococcush haemolytic and Staphylococcus hominis was high.No hospital vancomycin resistant was found.