The verification of abnormal whole blood cell classification with the Sysmex XE-2100 automated hematology analyzer

Objective To verify the accuracy of abnormal warning of the Sysmex XE-2100 automated hematology analyzer for whole blood cell count and classification.Methods Three hundred eighty-nine samples,which were determined to be abnormal by the analyzer,were stained and optical examined with microscope,and then the results were compared between the two methods.Results The sensitivity(%) of microscopic examination for classification of atypical lymphocyte(ATYP),nucleated red blood cell(NRBC),increase or decrease in mononuclear cells(M),immature granulocyte(IG),white blood cell count(WBC),lymphocyte count(L),microerythrocyte(MICRO) and macro-erythrocyte(MACRO) were 71.79,90.91,78.57,91.03,95.00,96.55 and 100.00,respectively,while the specificity(%) were 94.29,98.41,98.06,91.03,99.31,99.44 and 99.13,respectively.Conclusions The microscopic examination based on the IP information provided by the Sysmex XE-2100 and the information of patients can accurately screen positive samples.The combination of the two methods can provide timely,accurate,and reliable laboratory data for the clinicians.